A post-doctoral position is open in Dr. Robert Chapkin’s laboratory at Texas A&M University in the NIH-funded Integrative Nutrition & Complex Diseases Program. The laboratory is focused on environmental/nutritional modulation of stem cell biology, cancer biology, membrane biology, and cellular signal processing. One of the main current directions is the development of new tools to study the effects of environmental and microbial bioactive molecules on gut stem cell biology and chronic diseases. Our lab infrastructure includes: Flow cytometry single cell imaging, cell sorting and 3D mouse and human organoid cell culture, cell biology imaging (FLIM, FRET, TIRF) microscopy, super-resolution microscopy, metabolic profiling, epigenetics expertise (RNA Seq, ChIP Seq, microRNA analysis, systems biology) among others. Signaling pathways of interest include Wnt signaling, lipid rafts/cytoskeletal interaction, AhR, p53 and EGFR/Ras-dependent signaling.
Active projects in the lab include:
Effects of environmental and microbial-derived compounds on aryl hydrocarbon mediated gut stem cell function and cancer risk.
The impact of dietary and microbial bioactives on lipid and protooncogene nanoclustering in model membranes and in vivo (Drosophila, mouse and human organoid models).
Systems biology and predictive modeling for microbial and host intestinal responses.
The successful candidate must have a PhD degree in cell biology, biochemistry, nutrition, systems biology or relevant field. The candidate must be highly motivated, comfortable with technical challenges and problem solving and able to work collaboratively. Experience with fluorescence microscopy is an asset. Competitive salary and benefits are available commensurate with experience. Fluent English, a track record of strong publications, and a cooperative attitude are a must for this position.
The Chapkin lab has been continuously funded by NIH for 30 years. For more information about the lab see: http://chapkinlab.tamu.eduhttp://www.ncbi.nlm.nih.gov/sites/myncbi/robert.chapkin.1/bibliography/41155665/public/?sort=date&direction=descending
Please submit your CV and statement of current interests to Dr. Robert Chapkin, firstname.lastname@example.org
Internal Number: 1024
About Texas A&M University
Dr. Robert S. Chapkin (Mentor) is a nutritional biochemist in the Program in Integrative Nutrition & Complex Diseases and the Center for Translational Environmental Health Research at Texas A&M University. He currently holds appointments in the Departments of Nutrition & Food Science, Biochemistry & Biophysics, and Microbial & Molecular Pathogenesis. He received his BS in Nutrition and Biochemistry from the University of Guelph, Ontario, Canada; an MS in Nutrition from the University of Guelph, and a PhD in Nutrition and Physiological Chemistry from the University of California-Davis in 1986. After completing a postdoctoral fellowship in Cancer Biology in the School of Medicine at the University of California-Davis in 1988, he joined the faculty at Texas A&M University. Dr. Chapkin is currently a Distinguished Professor, Regents Professor and University Faculty Fellow, and Deputy Director – NIEHS Center for Translational Environmental Health Research (CTEHR). During the past 25 years he has published over 200 peer-reviewed articles in nutrition, cancer biology and immunology. Dr. Chapkin works with students and post-docs to obtain NIH/NSERC/foreign national scholarship funding, and is strongly supported by the National Institutes of Health.